The rom-com anime series will air this October.
The sweet romantic comedy anime series “My Friend's Little Sister Has It In for Me!”, based on Ghost Mikawa’s light novel series of the same name, just released a new trailer. Previously, the main cast and release window of October 2025 was confirmed by the official website and X (formerly Twitter) account of the series. The new trailer highlights the voice actors and gives us a glimpse of what’s to come.
My Friend’s Little Sister Has It In For Me! cast and staff details
The main cast of the anime comprises of:
- Iroha Kohinata voiced by Sayumi Suzushiro (Kei Shirogane in Kaguya-sama: Love Is War?, Nijika Ijichi in Bocchi the Rock!)
- Akiteru Oboshi voiced by Haruki Ishiya (Alex in Banana Fish, Jun Yagami in Salaryman’s Club)
- Mashiro Tsukinomori voiced by Tomori Kusunoki (Neiru Aonuma and Airu Aonuma in Wonder Egg Priority, Makima in Chainsaw Man)
- Ozuma Kohinata voiced by Soma Saito (Hyōma Chigiri in Blue Lock, Tadashi Yamaguchi in Haikyu!!)
- Sumire Kageishi voiced by Kana Hanazawa (Mitsuri Kanroji in Demon Slayer, Sakura Hanazono in Maid Sama!)
Studio BLADE is animating and producing the series with Kazuomi Koga directing it. Toko Machia handles series composition while Katsuyuki Sato designs the characters. Tsugumi Tanaka, Kaho Sawada, Kanade Sakuma and Hanae Nakamura are working on the show’s music together. The original light novel series, written by Ghost Mikawa and illustrated by Tomari began publishing in 2019. A manga adaptation by Hira Hiraoka began in the same year. J-Novel Club publishes the novel series in English and describes the story as:
If a girl teases you, that means she likes you! Unfortunately, Akiteru knows from experience that isn’t the case. Because every girl he interacts with shows him nothing but scorn, and he’s not scored a single date from it! Luckily, he’s more concerned with securing a spot for him and his game-development buddies at his uncle’s business. But when his uncle throws him a condition that involves playing the part of his daughter’s boyfriend, Akiteru has no choice but to take it. What will his best friend’s sister Iroha, who bullies him relentlessly, think of the news?